Product Name:Tideglusib

CAS No:865854-05-3

MF:C19H14N2O2S

MW:334.39166

pKa:-1.51±0.20(Predicted)

Density:1.393

Color:white to beige

Boiling Point:511.3±43.0 °C(Predicted)

Storage:2-8°C

Solubility:DMSO: >15mg/mL

Tideglusib (NP-12, NP031112) is a potent, selective and irreversible small molecule non-ATP-competitive glycogen synthase kinase 3 (GSK-3) inhibitor.. Other GSK inhibitors. There are few classes of GSK-inhibitors, including lithium (Martinez et al., 2011), the small peptide L803mts10, and members of the thiazolidinedione family, containing non-competitive inhibitors of GSK-3, such as TDZD-8.Tideglusib is a GSK-3 inhibitor currently in phase II clinical trials for the treatment of Alzheimer disease and progressive supranuclear palsy.